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Fosfomycin 3gm sachet (Monurol), a single-dose antibiotic, is a popular choice for treating uncomplicated urinary tract infections (UTIs) in women. Here's a detailed exploration of how long fosfomycin takes to work and other aspects of this medication.
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Mechanism of Action:
Fosfomycin works by interfering with the cell wall synthesis of susceptible bacteria, preventing them from growing and multiplying. This rapid action helps eliminate the bacteria causing the UTI.
How Long Does Fosfomycin Take to Work?
Fosfomycin boasts a fast onset of action. Studies show that:
High urine concentration: Within 2-4 hours of taking a single 3g dose of fosfomycin, high concentrations of the medication are present in the urine.
Bacterial elimination: This high concentration effectively eliminates susceptible bacteria, leading to symptom improvement.
Clinical Picture:
While the exact timeframe for symptom relief can vary slightly depending on the individual, most people experience improvement within:
2 to 3 days: Many people notice a significant reduction in UTI symptoms like burning urination, urgency, and frequency within this timeframe.
Continued improvement: Even after symptoms subside, fosfomycin remains active in the urinary tract at lower concentrations for up to 72 hours, helping to ensure complete eradication of the infection.