The original Ratchet & Clank PS2 game from 2002 running on PCSX2 emulator.
PCSX2 fully supports both Reshade and Sweetfx. It also has GSDX_FX included, which is a basic shader similar to earlier versions of Reshade.
Reshade and Sweetfx require DX9 or DX11 plugins in order to work but GSDX_FX works with OpenGL and DX11.